IVF clinical trials San Antonio

Houston Fertility Institute (HFI) is proud to announce its participation in a clinical trial for a new investigational in vitro fertilization (IVF) treatment. This trial, the Thrive-IVF Research Study, is for patients who have previously not been successful with IVF. HFI is one of 20 participating sites chosen from around the country.

What is IVF?

In vitro fertilization is a procedure in which oocytes (eggs) are retrieved from the ovaries and then fertilized by sperm in the laboratory. In nearly all cases, women receive medications to allow the ovaries to produce multiple eggs. After fertilization, the resulting embryos are grown in culture for three to five days, and then embryo(s) are transferred into the uterus. Extra embryos are frozen (cryopreserved) for later use. The process of transferring cryopreserved embryo is referred to as an “FET”.

Who is eligible to participate in this study?

The majority of women undergoing IVF between the ages of 21 and 38 years will to achieve a pregnancy and deliver a healthy baby. Unfortunately, some women will not have a successful pregnancy despite several attempts with IVF and FET.

This study is evaluating patients between 21 and 38 years of age who have not had a successful pregnancy with IVF and FET. Women who have had good quality embryos transferred in three cycles and have not had a successful pregnancy are being recruited to participate. Two of the cycles must be in a “fresh” IVF cycle. Patients who have had negative pregnancy tests or early pregnancy losses in these cycles are eligible.

What is the study examining?

This study is examining the ability of a chemical called granulocyte colony stimulating factor (G-CSF) to increase ongoing pregnancy rates in patients who have not been successful in previous IVF cycles. This chemical is normally produced by white blood cells (also called leukocytes) in the body. The G-CSF used in this study is produced in the laboratory and is called “NT100″. NT100 is an investigational drug.

Preliminary studies have shown that G-CSF, when added to culture medium, may improve embryo quality. In addition, initial studies in other similar G-CSF products have suggested that administration of G-CSF may improve pregnancy rates in patients who have failed to have embryo implantation and may also improve ongoing pregnancy rates in patients who have had early pregnancy losses.

What is provided by the study sponsor?

Eligible patients will receive the IVF cycle, including study-related medications at no cost. Patients electing to participate will be randomly allocated to one of two groups. One group will receive the study medication (NT100), while the other group will receive a placebo (inactive) medication.

Dr Craig Witz
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Popular Q&A

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How much is ivf in San Antonio Texas?

And are you able to be awake when they retrieve the eggs and how many day do you have to inject your body with hormones

My guess is that the cost of ivf in San Antonio is in par with the cost of ivf anywhere else. One cycle typically runs $10k-$15k. No, usually you are asleep during egg retrieval. As far as how many days of injections you will need... depends on how your body responses to the hormones. It usually takes anywhere from 8-12 days of injectable hormones to get your eggs to grow (these injections are done in your abdomen). Then you will have 1 trigger shot to get you to ovulate (done in your butt) and then you will have daily progesterone injections (in your butt) until you are about 10 weeks …

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