Clinical trial results with oncolytic virotherapy

Clinical trial results with oncolytic virotherapy: a century of promise, a decade of progress

Ta-Chiang Liu, Evanthia Galanis and David Kirn

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Figure 1. Schematic of oncolytic virotherapy mechanism of action: viral replication, cell killing, virus release and spread within cancer tissue but not normal tissues.

Reproduced from Kirn D et al. (2001) Nat Med : 781–787.

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